2-Butyl-4-chloro-7-iodo-5H-pyrrolo[3,2-d]pyrimidine → 2-Butyl-4-chloro-7-iodo-6-methyl-5H-pyrrolo[3,2-d]pyrimidine

HRID 1487249노트

반응식

HRID 1487249 반응식
[CH2:1]([C:5]1[N:6]=[C:7]([Cl:15])[C:8]2[NH:13][CH:12]=[C:11]([I:14])[C:9]=2[N:10]=1)[CH2:2][CH2:3][CH3:4].[CH2:16](C1N=C(Cl)C2NC(C)=CC=2N=1)CCC>>[CH2:1]([C:5]1[N:6]=[C:7]([Cl:15])[C:8]2[NH:13][C:12]([CH3:16])=[C:11]([I:14])[C:9]=2[N:10]=1)[CH2:2][CH2:3][CH3:4]

참가 물질

3

반응물 2

HCID 1183828472-Butyl-4-chloro-7-iodo-5H-pyrrolo[3,2-d]pyrimidineHCID 1184166922-Butyl-4-chloro-6-methyl-5H-pyrrolo[3,2-d]pyrimidine

생성물 1

HCID 1184166162-Butyl-4-chloro-7-iodo-6-methyl-5H-pyrrolo[3,2-d]pyrimidine

실험 절차

Prepared similarly to Intermediate 4 from. 2-butyl-4-chloro-6-methyl-5H-pyrrolo[3,2-d]pyrimidine.

출처 및 근거

ORD 기록
ord-d0e84b2d93fa4076a1369dc7fdf3fc50
출처 데이터셋
uspto-grants-2016_08
특허 번호
US09428512B2

반응 노트

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