5-((Benzyloxy)methyl)-2-butyl-4-chloro-7-iodo-5H-pyrrolo[3,2-d]pyrimidine → 5-((Benzyloxy)methyl)-2-butyl-4-chloro-7-iodo-6-methyl-5H-pyrrolo[3,2-d]pyrimidine

HRID 1487250노트

반응식

HRID 1487250 반응식
[CH2:1]([O:8][CH2:9][N:10]1[C:18]2[C:17]([Cl:19])=[N:16][C:15]([CH2:20][CH2:21][CH2:22][CH3:23])=[N:14][C:13]=2[C:12]([I:24])=[CH:11]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:25](C1N=C(Cl)C2NC(C)=C(I)C=2N=1)CCC>>[CH2:1]([O:8][CH2:9][N:10]1[C:18]2[C:17]([Cl:19])=[N:16][C:15]([CH2:20][CH2:21][CH2:22][CH3:23])=[N:14][C:13]=2[C:12]([I:24])=[C:11]1[CH3:25])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 1183828495-((Benzyloxy)methyl)-2-butyl-4-chloro-7-iodo-5H-pyrrolo[3,2-d]pyrimidineHCID 1184166162-Butyl-4-chloro-7-iodo-6-methyl-5H-pyrrolo[3,2-d]pyrimidine

생성물 1

HCID 1184166085-((Benzyloxy)methyl)-2-butyl-4-chloro-7-iodo-6-methyl-5H-pyrrolo[3,2-d]pyrimidine

실험 절차

Prepared similarly to Intermediate 5 from 2-butyl-4-chloro-7-iodo-6-methyl-5H-pyrrolo[3,2-d]pyrimidine

출처 및 근거

ORD 기록
ord-5a0a7bf63cac46adace90a03ff96782f
출처 데이터셋
uspto-grants-2016_08
특허 번호
US09428512B2

반응 노트

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