Tert-butyl 4-(4-cyanophenyl)piperidine-1-carboxylate → Tert-butyl 4-(imidazo[1,5-a]pyridin-7-yl)piperidine-1-carboxylate

HRID 1487890노트

반응식

HRID 1487890 반응식
C([C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:14][CH2:13][N:12]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:11][CH2:10]2)=[CH:5][CH:4]=1)#N.BrC1C=C[N:26]2[CH:29]=[N:30]C=C2C=1>>[CH:3]1[N:26]=[CH:29][N:30]2[CH:4]=[CH:5][C:6]([CH:9]3[CH2:10][CH2:11][N:12]([C:15]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:16])[CH2:13][CH2:14]3)=[CH:7][C:8]=12

참가 물질

3

반응물 2

HCID 22492960Tert-butyl 4-(4-cyanophenyl)piperidine-1-carboxylateHCID 668886407-Bromoimidazo(1,5-a)pyridine2회

생성물 1

HCID 90033879Tert-butyl 4-(imidazo[1,5-a]pyridin-7-yl)piperidine-1-carboxylate

실험 절차

The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 1.1, except 7-bromoimidazo[1,5-a]pyridine (compound 39.3) was used in place of 4-bromobenzonitrile.

출처 및 근거

ORD 기록
ord-b643fa1f81dd445cabd05bd9feed9306
출처 데이터셋
uspto-grants-2016_08
특허 번호
US09428502B2

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