Methyl 5-cyano-4-cyclobutyl-2-methylbenzoate → Methyl 5-cyano-4-fluoro-2-methylbenzoate
반응식
[C:1]([C:3]1[C:4](C2CCC2)=[CH:5][C:6]([CH3:13])=[C:7]([CH:12]=1)[C:8]([O:10][CH3:11])=[O:9])#[N:2].[F:18]C1C(I)=CC(C(OC)=O)=C(C)C=1.C1(C2C(I)=CC(C(OC)=O)=C(C)C=2)CCC1>>[C:1]([C:3]1[C:4]([F:18])=[CH:5][C:6]([CH3:13])=[C:7]([CH:12]=1)[C:8]([O:10][CH3:11])=[O:9])#[N:2]참가 물질
4
실험 절차
The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 6.4, except methyl 4-fluoro-5-iodo-2-methylbenzoate (compound 101.2) was used in place of methyl 4-cyclobutyl-5-iodo-2-methylbenzoate (compound 6.3).
출처 및 근거
- ORD 기록
- ord-f6b5b83a7cd54023801ce8f946bf6df2
- 출처 데이터셋
- uspto-grants-2016_08
- 특허 번호
- US09428502B2
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