Methyl 5-(4-cyano-2-(3-methyloxetan-3-yl)-1H-imidazol-5-yl)-2,4-dimethylbenzoate → 5-(4-Cyano-2-(3-methyloxetan-3-yl)-1H-imidazol-5-yl)-2,4-dimethylbenzoic acid
반응식
CC1NC(C2C=C(C=CC=2C)C(O)=O)=C(C)N=1.[C:18]([C:20]1[N:21]=[C:22]([C:37]2([CH3:41])[CH2:40][O:39][CH2:38]2)[NH:23][C:24]=1[C:25]1[C:26]([CH3:36])=[CH:27][C:28]([CH3:35])=[C:29]([CH:34]=1)[C:30]([O:32]C)=[O:31])#[N:19].CC1NC(C2C=C(C=CC=2C)C(OC)=O)=C(C)N=1>>[C:18]([C:20]1[N:21]=[C:22]([C:37]2([CH3:41])[CH2:40][O:39][CH2:38]2)[NH:23][C:24]=1[C:25]1[C:26]([CH3:36])=[CH:27][C:28]([CH3:35])=[C:29]([CH:34]=1)[C:30]([OH:32])=[O:31])#[N:19]참가 물질
4
실험 절차
The title compound was prepared using standard chemical manipulations and procedures similar to those used for the preparation of compound 5.7, except methyl 5-(4-cyano-2-(3-methyloxetan-3-yl)-1H-imidazol-5-yl)-2,4-dimethylbenzoate (compound 203.1) was used in place of methyl 3-(2,4-dimethyl-1H-imidazol-5-yl)-4-methylbenzoate (compound 5.6). m/z (ES+) 312 (M+H)+.