4,4,4-Trifluorobutan-2-one → 4,4,4-Trifluoro-2-oxobutanal

HRID 1488232노트

반응식

HRID 1488232 반응식
CC(O)=[O:3].O.[F:6][C:7]([F:13])([F:12])[CH2:8][C:9](=[O:11])[CH3:10]>O1CCOCC1>[F:6][C:7]([F:13])([F:12])[CH2:8][C:9](=[O:11])[CH:10]=[O:3]

참가 물질

4

반응물 2

HCID 5390014,4,4-Trifluorobutan-2-oneHCID 21899381Acetic acid--water (1/1)

생성물 1

HCID 900219564,4,4-Trifluoro-2-oxobutanal

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

반응 조건

온도
100 °C

실험 절차

To a solution of SeO2 (4.23 g, 38.1 mmol) in dioxane (25 mL) was added AcOH/H2O (1 mL/1 mL). 4,4,4-Trifluorobutan-2-one (3.81 mL, 31.7 mmol) was added dropwise to the above reaction mixture. The resulting solution was stirred overnight at 100° C. The solution was used in the next step without any further work-up or purification.

후처리

  1. customThe solution was used in the next step without any further work-up or purification

출처 및 근거

ORD 기록
ord-ffba34d1e2674065bd8c7ade01904ce5
출처 데이터셋
uspto-grants-2016_08
특허 번호
US09428502B2

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