Bromobenzene → N-(6-chloro-3-pyridazinyl)-5-fluoro-1,6-dimethyl-4-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide

반응식

[Br:25][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1.[F:1][c:2]1[c:3]([OH:16])[c:4]([C:11]([O:13][CH2:12][CH3:14])=[O:15])[c:5](=[O:10])[n:6]([CH3:9])[c:7]1[CH3:8].[NH2:17][c:18]1[n:19][n:20][c:21]([Cl:24])[cH:22][cH:23]1>>[F:1][c:2]1[c:3]([OH:16])[c:4]([C:11](=[O:13])[NH:17][c:18]2[n:19][n:20][c:21]([Cl:24])[cH:22][cH:23]2)[c:5](=[O:10])[n:6]([CH3:9])[c:7]1[CH3:8]

참가 물질

반응물 3

HCID 7961Bromobenzene

HCID 216436-Amino-3-chloropyridazine

HCID 57619577Ethyl 5-fluoro-1,6-dimethyl-4-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxylate

생성물 1

HCID 57672125N-(6-chloro-3-pyridazinyl)-5-fluoro-1,6-dimethyl-4-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxamide

출처 및 근거

ORD 기록: ord-eddbecab6d0e41cba865dd29ea31fe13
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

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