1,2-Dibromoethane → HCID 22905874, 화합물

HRID 1488572노트

반응식

HRID 1488572 반응식
[Br:1][C:2]1[CH:7]=[C:6]([Br:8])[CH:5]=[C:4]([C:9]([CH3:12])([CH3:11])[CH3:10])[C:3]=1[OH:13].[Br:14][CH2:15][CH2:16]Br.C([O-])([O-])=O.[K+].[K+]>CC(C)=O>[Br:1][C:2]1[CH:7]=[C:6]([Br:8])[CH:5]=[C:4]([C:9]([CH3:10])([CH3:12])[CH3:11])[C:3]=1[O:13][CH2:16][CH2:15][Br:14]

참가 물질

5

반응물 3

HCID 78391,2-DibromoethaneHCID 11430Potassium CarbonateHCID 719757AKOS BBS-00008108

생성물 1

HCID 22905874HCID 22905874, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

To a solution of 2,4-dibromo-6-tert-butylphenol (5.00 g, 16.2 mmol) in acetone (70 mL) is added 1,2-dibromoethane (2.80 mL, 32.5 mmol) and K2CO3 (6.70 g, 48.7 mmol). The mixture is heated at reflux for 14 h, and then is filtered and evaporated. The residue is purified by chromatography over SiO2 eluting 15 with hexanes. The resulting oil is distilled to give 1,5-dibromo-(2-bromoethoxy)-3-tert-butylbenzene as a pale yellow oil.

후처리

  1. temperatureThe mixture is heated
  2. temperatureat reflux for 14 h
  3. filtrationis filtered
  4. customevaporated
  5. customThe residue is purified by chromatography over SiO2 eluting 15 with hexanes
  6. distillationThe resulting oil is distilled

출처 및 근거

ORD 기록
ord-105bdd4002844b1894b2e58a70facaa6
출처 데이터셋
uspto-grants-1997_10
특허 번호
US05674891

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