2-Bromo-2,3-dihydro-4-fluoro-1H-inden-1-one → 2-Bromo-4,6-dichloro-1-indanone
반응식
[Br:1]C1CC2C(=CC=CC=2F)C1=O.[Cl:13][C:14]1[CH:22]=[C:21]([Cl:23])[CH:20]=[C:19]2[C:15]=1[CH2:16][CH2:17][C:18]2=[O:24]>[Cu](Br)Br.O1CCOCC1>[Br:1][CH:17]1[CH2:16][C:15]2[C:19](=[CH:20][C:21]([Cl:23])=[CH:22][C:14]=2[Cl:13])[C:18]1=[O:24]참가 물질
5
실험 절차
The 2-bromo-4,6-dichloro-1-indanone is prepared as in Example 14 for the preparation of 2-bromo-4-fluoro-1-indanone but starting with 21.6 g of 4,6-dichloro-1-indanone, 63.56 g of copper bromide and 690 ml of dioxane. 14.5 g of 2-bromo-4,6-dichloro-1-indanone are obtained which melt at 80° C.
출처 및 근거
- ORD 기록
- ord-fa248855844946139a2b36b84e6193f0
- 출처 데이터셋
- uspto-grants-1997_10
- 특허 번호
- US05677306
반응 노트
불러오는 중…