HCID 22902236, 화합물 → HCID 22902199, 화합물
반응식
COC([NH:5][C:6]12[CH2:14][N:13](C(OC)=O)[CH2:12][CH:11]1[CH:10]=[CH:9][CH:8]=[CH:7]2)=O>O>[CH2:12]1[CH:11]2[C:6]([NH2:5])([CH:7]=[CH:8][CH:9]=[CH:10]2)[CH2:14][NH:13]1참가 물질
3
시약·촉매·용매 1
실험 절차
20 g of crude methyl 1-methoxycarbonylamino-8-azabicyclo[4.3.0]nona-2,4-diene-8-carboxylate are heated with 75 g (0.235 mol) of Ba(OH)2.8 H2O in 250 ml of water overnight under reflux. The BaCO3 is filtered off with suction, the filtrate is concentrated and the salt residues are boiled three times with 1,4-dioxane. The dioxane solutions are concentrated and the residue is distilled. Yield: 5 g (43.9% of theory based on Step D), boiling point: 65° C./0.2 mbar.
후처리
- filtrationThe BaCO3 is filtered off with suction
- concentrationthe filtrate is concentrated
- concentrationThe dioxane solutions are concentrated
- distillationthe residue is distilled
출처 및 근거
- ORD 기록
- ord-8bf60291ce6f49f58192a3707e6d10fc
- 출처 데이터셋
- uspto-grants-1997_10
- 특허 번호
- US05679689
반응 노트
불러오는 중…