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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1490353생성일: 2026년 10월 27일

(4-Nitrophenyl)methyl (2-mercaptoethyl)carbamate → 4-Nitrobenzyl (1R, 5S,6S)-6-[1(R)-t-butyldimethylsilyloxyethyl]-1-methyl-2-[2-(4-nitrobenzyloxycarbonyl)aminoethylthio]-1-carbapen-2-em-3-carboxylate

https://huagongshe.com/reaction/1490353

반응식

참여 물질

역할이름HCID투입량
반응물(4-Nitrophenyl)methyl (2-mercaptoethyl)carbamateHCID 3017625—
반응물4-nitrobenzyl (1R, 5S,6S)-2-(2-diethylcarbamoylphenylsulfinyl)-1-methyl-6-[1(R)-t-butyldimethylsilyloxyethyl]-1-carbapen-2-em-3-carboxylateHCID 11028830—
생성물4-Nitrobenzyl (1R, 5S,6S)-6-[1(R)-t-butyldimethylsilyloxyethyl]-1-methyl-2-[2-(4-nitrobenzyloxycarbonyl)aminoethylthio]-1-carbapen-2-em-3-carboxylateHCID 1100704983%

반응 단계

Following a procedure similar to that described in Example 21(b), but using 4-nitrobenzyl (1R, 5S,6S)-2-(2-diethylcarbamoylphenylsulfinyl)-1-methyl-6-[1(R)-t-butyldimethylsilyloxyethyl]-1-carbapen-2-em-3-carboxylate (prepared as described in Example 39) and 2-(4-nitrobenzyloxycarbonyl)aminoethylmercaptan as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 83%.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05681951
출처 데이터셋uspto-grants-1997_10
ORD IDord-2c0f70b76a31488f9dd473beba535242
출처 메모uspto-grants-1997_10