5-Bromo-2-methyl-1,3-benzoxazole → 5-Bromo-2-methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazole

HRID 1490431노트

반응식

HRID 1490431 반응식
Cc1nc2cc(Br)ccc2o1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1cnc2c(ccc3c(C)c(C)cnc32)c1C.[Ir].[Ir]>Cc1nc2cc(Br)cc(B3OC(C)(C)C(C)(C)O3)c2o1

참가 물질

6

반응물 1

HCID 101045995-Bromo-2-methyl-1,3-benzoxazole

생성물 1

HCID 1018796705-Bromo-2-methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazole수율 86%

시약·촉매·용매 4

HCID 742653,4,7,8-Tetramethyl-1,10-phenanthroline시약HCID 2733548Bis(pinacolato)diborane시약HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium촉매HCID 8028Tetrahydrofuran용매

반응 조건

온도
25 °C

출처 및 근거

ORD 기록
ord-1988b96e09e44dcaa2b3003a8dbd7f6d
출처 데이터셋
Borylation dataset from Roche

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