1-Boc-7-azaindole → tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine-1-carboxylate

HRID 1490474노트

반응식

HRID 1490474 반응식
CC(C)(C)OC(=O)n1ccc2cccnc21>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1cnc2c(ccc3c(C)c(C)cnc32)c1C.[Ir].[Ir]>CC(C)(C)OC(=O)n1cc(B2OC(C)(C)C(C)(C)O2)c2cccnc21

참가 물질

6

반응물 1

HCID 214810821-Boc-7-azaindole

생성물 1

HCID 53217196tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine-1-carboxylate수율 70%

시약·촉매·용매 4

HCID 742653,4,7,8-Tetramethyl-1,10-phenanthroline시약HCID 2733548Bis(pinacolato)diborane시약HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium촉매HCID 8028Tetrahydrofuran용매

반응 조건

온도
25 °C

출처 및 근거

ORD 기록
ord-a24b875fa55243e28149d7553d382fd0
출처 데이터셋
Borylation dataset from Roche

반응 노트

불러오는 중…