1-(Triisopropylsilyl)indole → HCID 11395451, 화합물
반응식
CC(C)[Si](C(C)C)(C(C)C)n1ccc2ccccc21>B1Oc2ccccc2O1.C1=CC2C=CC1C2.CC(C)(O)C(C)(C)O.CCN(CC)CC.Cc1ccccc1.Fc1c(F)c(F)c(B(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F>CC(C)[Si](C(C)C)(C(C)C)n1cc(B2OC(C)(C)C(C)(C)O2)c2ccccc21참가 물질
8
반응 조건
- 온도
- 25 °C
실험 절차
Prepared from N-(triisopropylsilyl)-1H-indole (4a, 27.4 mg, 0.100 mmol, 1.00 equiv), catBH (24.0 mg, 0.200 mmol, 2.00 equiv), norbornene (18.8 mg, 0.100 mmol, 1.00 equiv) and B(C6F5)3 (5.1 mg, 0.010 mmol, 0.10 equiv) according to GP 3. The title compound was purified by flash column chromatography using cyclohexane/EtOAc/Et3N (30/1/1) as eluent to afford 3j (24.4 mg, 61%) as a white solid.
출처 및 근거
- ORD 기록
- ord-15f394501a194234ab9754975d2d9bdd
- 출처 데이터셋
- Borylation dataset from Roche
반응 노트
불러오는 중…
