2-Methoxythiophene → 2-(5-Methoxythiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

온도

25 °C

Prepared from 2-methoxythiophene (4j, 114.2 mg, 1.00 mmol, 1.00 equiv), catBH (240 mg, 2.00 mmol, 2.00 equiv), N,N,4-trimethylaniline (1f, 13.5 mg, 0.10 mmol, 0.10 equiv), norbornene (94.0 mg, 1.00 mmol, 1.00 equiv), and B(C6F5)3 (51.2 mg, 0.10 mmol, 0.10 equiv) according to GP 3. The title compound was purified by flash column chromatography using cyclohexane/EtOAc/Et3N (30/1/1) as eluent to afford 6j[S5] (96.8 mg, 40%) as a colorless liquid.

ORD 기록

ord-9284ce38474e4c6197f167142a799d26

출처 데이터셋

Borylation dataset from Roche

DOI

10.1002/anie.201611536