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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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Benzene, 1-chloro-4-(1,1-dimethylethyl)- → HCID 129946666, 화합물

HRID 1490568
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HRID 1490568 반응식
CC(C)(C)c1ccc(Cl)cc1>C1=CCCC=CCC1.C1=CCCC=CCC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COC1CCCC1.C[OH2+].C[OH2+].[Ir].[Ir].c1ccc(N2B(B3Nc4ccccc4N3c3ccccn3)Nc3ccccc32)nc1>CC(C)(C)c1ccc(Cl)c(B2OC(C)(C)C(C)(C)O2)c1
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참가 물질

6

반응물 1

HCID 77594Benzene, 1-chloro-4-(1,1-dimethylethyl)-

생성물 1

HCID 129946666HCID 129946666, 화합물수율 80%

시약·촉매·용매 4

HCID 2733548Bis(pinacolato)diborane시약HCID 1223807993-pyridin-2-yl-2-(3-pyridin-2-yl-1H-1,3,2-benzodiazaborol-2-yl)-1H-1,3,2-benzodiazaborole시약HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium촉매

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온도
100 °C

실험 절차

The general procedure A was followed using 1-(tert-butyl)-4-chlorobenzene (79.1 ul, 0.5 mmol) and B2pin2 (126.9 mg, 0.5 mmol, 1.0 eq.) as starting material. The resulting mixture was allowed to stir 16 hours at 100 oC. 5aa was obtained as white solid (118.0 mg, 80%) after purification by silica gel flash chromatography (EtOAc/PE=1:50 v/v). m.p.: 73-75 oC.

출처 및 근거

ORD 기록
ord-db591dda52a34d67a62a70de910a941f
출처 데이터셋
Borylation dataset from Roche
DOI
10.1021/jacs.5b05252

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이 페이지에서참가 물질반응 조건실험 절차출처 및 근거반응 노트
HCID 138539
Cyclopentyl methyl ether
용매