2-Methylindole → 2-Methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

HRID 1490582노트

반응식

HRID 1490582 반응식
Cc1cc2ccccc2[nH]1>C1=CCCC=CCC1.C1=CCCC=CCC1.CC(C)(C)c1ccnc(-c2cc(C(C)(C)C)ccn2)c1.CC1(C)OBOC1(C)C.CCCCCC.C[OH2+].C[OH2+].[Ir].[Ir]>Cc1cc2cccc(B3OC(C)(C)C(C)(C)O3)c2[nH]1

참가 물질

6

반응물 1

HCID 72242-Methylindole

생성물 1

HCID 249605942-Methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole수율 78%

시약·촉매·용매 4

HCID 27347684,4,5,5-Tetramethyl[1,3,2]dioxaborolane시약HCID 42491874,4'-Di-tert-butyl-2,2'-bipyridyl시약HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium촉매HCID 8058Hexane용매

반응 조건

온도
60 °C

출처 및 근거

ORD 기록
ord-c853cc0bd9df4c4bb6cf97a618a4e94a
출처 데이터셋
Borylation dataset from Roche

반응 노트

불러오는 중…