1-Methylpyrrole → 1-Methyl-1H-pyrrole-2-boronic acid, pinacol ester

HRID 1490644노트

반응식

HRID 1490644 반응식
Cn1cccc1>CC1(C)OBOC1(C)C.CC[NH+](CC)c1ccccc1[B-](F)(F)F>Cn1ccc(B2OC(C)(C)C(C)(C)O2)c1.Cn1cccc1B1OC(C)(C)C(C)(C)O1

참가 물질

5

반응물 1

HCID 73041-Methylpyrrole

생성물 2

HCID 441187731-Methyl-1H-pyrrole-2-boronic acid, pinacol ester수율 91%HCID 532171481-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole수율 2%

시약·촉매·용매 2

HCID 27347684,4,5,5-Tetramethyl[1,3,2]dioxaborolane시약HCID 139125631[2-(Diethylazaniumyl)phenyl]-trifluoroboranuide촉매

반응 조건

온도
80 °C

출처 및 근거

ORD 기록
ord-17454c9359b344d689e48e8a67a3b3b9
출처 데이터셋
Borylation dataset from Roche

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