Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tert-Butylamine → tert-Butyl-[3-(2-chloro-pyrimidin-4-yl)-benzyl]-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tert-Butylamine | HCID 6385 | — |
| 반응물 | 3-(2-Chloro-pyrimidin-4-yl)-benzaldehyde | HCID 24901965 | — |
| 생성물 | tert-Butyl-[3-(2-chloro-pyrimidin-4-yl)-benzyl]-amine | HCID 86603310 | 97% |
반응 단계
3-(2-Chloro-pyrimidin-4-yl)-benzaldehyde (intermediate 1) and tert butylamine were coupled by procedure B. The yield was 97%. LC-MS showed the product had the expected M+H+ of 276. 1H NMR (Varian 300 MHz, CDCl3, shifts relative to the solvent peak at 7.24 ppm) 8.6 (d, 1H) 8.1 (s, 1H) 7.9 (d, 1H) 7.6 (d, 1H) 7.5 (m, 2H) 1.2 (s, 9H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07732444B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-4b4178151fca419dac819ae8ff154559 |
| 출처 메모 | uspto-grants-2010_06 |