홈MCP워크벤치Skills
홈워크벤치알림마이페이지
llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
  1. 홈
  2. /반응

Ethyl 3-hydroxybenzoate → Ethyl 3-hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate

HRID 1490701
노트
인쇄 미리보기

반응식

HRID 1490701 반응식
CCOC(=O)c1cccc(O)c1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCCCC1.CC(C)(C)c1ccnc(-c2cc(C(C)(C)C)ccn2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.CC1(C)OBOC1(C)C.C[OH2+].C[OH2+].[Ir].[Ir]>CCOC(=O)c1cc(O)cc(B2OC(C)(C)C(C)(C)O2)c1.CCOC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)c(O)c1
참가 물질반응 조건출처 및 근거반응 노트

참가 물질

8

반응물 1

HCID 24522Ethyl 3-hydroxybenzoate

생성물 2

HCID 130066909Ethyl 3-hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate수율 82%HCID 131586531Ethyl 3-hydroxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate수율 18%

시약·촉매·용매 5

HCID 2733548Bis(pinacolato)diborane시약HCID 27347684,4,5,5-Tetramethyl[1,3,2]dioxaborolane시약HCID 42491874,4'-Di-tert-butyl-2,2'-bipyridyl시약HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium촉매HCID 8078Cyclohexane용매

반응 조건

온도
80 °C

출처 및 근거

ORD 기록
ord-243778d5f5a048b2bc156278d3a99182
출처 데이터셋
Borylation dataset from Roche
DOI
10.1021/jacs.7b02232

반응 노트

불러오는 중…

이 페이지에서참가 물질반응 조건출처 및 근거반응 노트