Ethyl 2-thenoate → Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carboxylate

HRID 1490708

반응식

HRID 1490708 반응식
CCOC(=O)c1cccs1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC(C)(C)O.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].O=c1ccc2cccc(-c3ccc(-c4ccccn4)nc3)c2[nH]1.[Ir].[Ir].[K]>CCOC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)s1

참가 물질

7

반응물 1

HCID 76052Ethyl 2-thenoate

생성물 1

HCID 46739336Ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carboxylate수율 93%

시약·촉매·용매 5

HCID 2733548Bis(pinacolato)diborane시약HCID 86639980Potassium tert-butoxide시약HCID 1646813858-([2,2'-bipyridin]-5-yl)quinolin-2(1H)-one시약HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium촉매HCID 8028Tetrahydrofuran용매

반응 조건

온도
80 °C

출처 및 근거

ORD 기록
ord-eb6d1b7c6fcb4f6987ce7b9722ad20c1
출처 데이터셋
Borylation dataset from Roche

연결된 노트

불러오는 중…