2-Trifluoromethoxy-benzoic acid ethyl ester → 4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-2-trifluoromethoxy-benzoic acid ethyl ester

HRID 1490714

반응식

HRID 1490714 반응식
CCOC(=O)c1ccccc1OC(F)(F)F>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC(C)(C)O.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].O=c1ccc2cccc(-c3ccc(-c4ccccn4)nc3)c2[nH]1.[Ir].[Ir].[K]>CCOC(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1OC(F)(F)F

참가 물질

7

반응물 1

HCID 447848832-Trifluoromethoxy-benzoic acid ethyl ester

생성물 1

HCID 1389856424-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-2-trifluoromethoxy-benzoic acid ethyl ester수율 89%

시약·촉매·용매 5

HCID 2733548Bis(pinacolato)diborane시약HCID 86639980Potassium tert-butoxide시약HCID 1646813858-([2,2'-bipyridin]-5-yl)quinolin-2(1H)-one시약HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium촉매HCID 8028Tetrahydrofuran용매

반응 조건

온도
80 °C

출처 및 근거

ORD 기록
ord-c19d6f692f684d14aba5b6396d47d7d1
출처 데이터셋
Borylation dataset from Roche

연결된 노트

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