HCID 3486232, 화합물 → 2-bromo-N,N-dihexyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

HRID 1490835노트

반응식

HRID 1490835 반응식
CCCCCCN(CCCCCC)C(=O)c1ccccc1Br>C1=CCCC=CCC1.C1=CCCC=CCC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1ccc(C)cc1.O=C(Nc1ccccc1-c1ccc(-c2ccccn2)nc1)NC1CCCCC1.[Ir].[Ir]>CCCCCCN(CCCCCC)C(=O)c1cc(B2OC(C)(C)C(C)(C)O2)ccc1Br.CCCCCCN(CCCCCC)C(=O)c1ccc(B2OC(C)(C)C(C)(C)O2)cc1Br

참가 물질

7

반응물 1

HCID 3486232HCID 3486232, 화합물

생성물 2

HCID 918207552-bromo-N,N-dihexyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide수율 85%HCID 1408473452-bromo-N,N-dihexyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide수율 11%

시약·촉매·용매 4

HCID 2733548Bis(pinacolato)diborane시약HCID 91820779HCID 91820779, 화합물시약HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium촉매HCID 7809P-Xylene용매

반응 조건

온도
25 °C

출처 및 근거

ORD 기록
ord-df28cc89a4e54a5b842991925a02c74f
출처 데이터셋
Borylation dataset from Roche

반응 노트

불러오는 중…