Benzamide, N,N-dihexyl-2-trifluoromethyl- → N,N-dihexyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzamide

HRID 1490839노트

반응식

HRID 1490839 반응식
CCCCCCN(CCCCCC)C(=O)c1ccccc1C(F)(F)F>C1=CCCC=CCC1.C1=CCCC=CCC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1ccc(C)cc1.O=C(Nc1ccccc1-c1ccc(-c2ccccn2)nc1)NC1CCCCC1.[Ir].[Ir]>CCCCCCN(CCCCCC)C(=O)c1cc(B2OC(C)(C)C(C)(C)O2)ccc1C(F)(F)F

참가 물질

6

반응물 1

HCID 533223Benzamide, N,N-dihexyl-2-trifluoromethyl-

생성물 1

HCID 91820762N,N-dihexyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)benzamide수율 96%

시약·촉매·용매 4

HCID 2733548Bis(pinacolato)diborane시약HCID 91820779HCID 91820779, 화합물시약HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium촉매HCID 7809P-Xylene용매

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온도
25 °C

출처 및 근거

ORD 기록
ord-29ed77fe0ab64fc4bc2210d6ed3a253f
출처 데이터셋
Borylation dataset from Roche

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