반응식
Cc1ccc2cc(Cl)ccc2n1>C1=CCCC=CCC1.C1=CCCC=CCC1.CC(C)(C)c1ccnc(-c2cc(C(C)(C)C)ccn2)c1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.COC(C)(C)C.C[OH2+].C[OH2+].[Ir].[Ir]>Cc1cc(B2OC(C)(C)C(C)(C)O2)c2cc(Cl)ccc2n1참가 물질
6
반응 조건
- 온도
- 100 °C
실험 절차
General procedure A was applied to 2-methyl-6-chloroquinoline (177 mg, 1.00mmol). Purification by silica gel flash-column chromatography with gradient elution of MeOH/DCM from 0.5 -12.5% over 25 column volumes, affording 6-chloro-2-methyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)quinoline as a white solid (239 mg, 79%); m.p.105 -106 °C;
출처 및 근거
- ORD 기록
- ord-9c583a7ebec9433296202e1a3feda655
- 출처 데이터셋
- Borylation dataset from Roche
연결된 노트
불러오는 중…