4-tert-butyl-N-methylbenzamide → HCID 178485327, 화합물

HRID 1491063노트

반응식

HRID 1491063 반응식
CNC(=O)c1ccc(C(C)(C)C)cc1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1[nH]c2c(NC(=O)c3ccc(-c4ccccn4)nc3)cccc2c1C.[Ir].[Ir]>CNC(=O)c1ccc(C(C)(C)C)cc1B1OC(C)(C)C(C)(C)O1

참가 물질

6

반응물 1

HCID 1812574-tert-butyl-N-methylbenzamide

생성물 1

HCID 178485327HCID 178485327, 화합물수율 41%

시약·촉매·용매 4

HCID 2733548Bis(pinacolato)diborane시약HCID 178433626HCID 178433626, 화합물시약HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium촉매HCID 8028Tetrahydrofuran용매

반응 조건

온도
60 °C

실험 절차

Isolated by chromatography using deactivated silica gel and ethyl acetate and petroleum ether (10:1 to 1:1) as the eluent.

출처 및 근거

ORD 기록
ord-8a014e76d53e4bd5920e1da16799d6de
출처 데이터셋
Borylation dataset from Roche

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