N-benzyl-3-bromobenzamide → HCID 178431025, 화합물

HRID 1491076노트

반응식

HRID 1491076 반응식
O=C(NCc1ccccc1)c1cccc(Br)c1>C1=CCCC=CCC1.C1=CCCC=CCC1.C1CCOC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1[nH]c2c(NC(=O)c3ccc(-c4ccccn4)nc3)cccc2c1C.[Ir].[Ir]>CC1(C)OB(c2ccc(Br)cc2C(=O)NCc2ccccc2)OC1(C)C

참가 물질

6

반응물 1

HCID 787882N-benzyl-3-bromobenzamide

생성물 1

HCID 178431025HCID 178431025, 화합물수율 64%

시약·촉매·용매 4

HCID 2733548Bis(pinacolato)diborane시약HCID 178433626HCID 178433626, 화합물시약HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium촉매HCID 8028Tetrahydrofuran용매

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온도
60 °C

실험 절차

Isolated by chromatography using deactivated silica gel and ethyl acetate and petroleum ether (10:0.5 to 10:3.0) as the eluent.

출처 및 근거

ORD 기록
ord-cdd2ed5a73de4ac98876f7b3bbb76f1f
출처 데이터셋
Borylation dataset from Roche

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