(Ethylthio)benzene → 2-(2-(Ethylthio)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

HRID 1491130

반응식

HRID 1491130 반응식
CCSc1ccccc1>C1=CCCC=CCC1.C1=CCCC=CCC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1ccc(C)cc1.FC(F)(F)C1COB(c2ccccc2-c2ccc(-c3ccccn3)nc2)O1.[Ir].[Ir]>CCSc1ccccc1B1OC(C)(C)C(C)(C)O1

참가 물질

6

반응물 1

HCID 12144(Ethylthio)benzene

생성물 1

HCID 1237879692-(2-(Ethylthio)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane수율 72%

시약·촉매·용매 4

HCID 2733548Bis(pinacolato)diborane시약HCID 1349566232-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine시약HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium촉매HCID 7809P-Xylene용매

반응 조건

온도
55 °C

실험 절차

Ligand 3f: The mixture of product (95 mg, 72% yield, ortho/meta + para = >30); ortho-borylated product 4b was obtained by further purification of the crude mixture by GPC (89 mg, 67% yield), white solid (mp. 48-50 oC)

출처 및 근거

ORD 기록
ord-b26c7059a55f4ed08e56318eb7eb563c
출처 데이터셋
Borylation dataset from Roche

연결된 노트

불러오는 중…