Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1491138생성일: 2026년 10월 26일
4-Bromothioanisole → 2-(5-Bromo-2-methylsulfanylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
https://huagongshe.com/reaction/1491138
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 4-Bromothioanisole | HCID 66037 | — |
| 시약 | Bis(pinacolato)diborane | HCID 2733548 | — |
| 시약 | 2-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine | HCID 134956623 | — |
| 촉매 | Bis(1,5-cyclooctadiene)dimethoxydiiridium | HCID 76001521 | — |
| 용매 | P-Xylene | HCID 7809 | — |
| 생성물 | 2-(5-Bromo-2-methylsulfanylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 132510261 | 74% |
| 생성물 | HCID 178503104 | HCID 178503104 | 11% |
반응 단계
Ligand 3f: A mixture of ortho- and meta-borylated products (139 mg, 85% yield, ortho/meta + para = 6.6); ortho-borylated product 4f was obtained by further purification by GPC (101 mg, 62% yield), yellow solid (mp. 88-90 oC)
출처 및 근거
| DOI | 10.1002/anie.201610041 |
|---|
| 출처 데이터셋 | Borylation dataset from Roche |
|---|
| ORD ID | ord-344f37acfe63498da614c14da31d0868 |
|---|
| 출처 메모 | Borylation dataset from Roche |
|---|
