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1-Chloro-3-(methylthio)benzene → HCID 138982779, 화합물

HRID 1491154
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HRID 1491154 반응식
CSc1cccc(Cl)c1>C1=CCCC=CCC1.C1=CCCC=CCC1.CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C.C[OH2+].C[OH2+].Cc1ccc(C)cc1.FC(F)(F)C1COB(c2ccccc2-c2ccc(-c3ccccn3)nc2)O1.[Ir].[Ir]>CSc1cc(Cl)cc(B2OC(C)(C)C(C)(C)O2)c1.CSc1cc(Cl)ccc1B1OC(C)(C)C(C)(C)O1
참가 물질반응 조건실험 절차출처 및 근거반응 노트

참가 물질

7

반응물 1

HCID 975851-Chloro-3-(methylthio)benzene

생성물 2

HCID 532172452-(3-Chloro-5-(methylthio)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane수율 10%HCID 138982779HCID 138982779, 화합물수율 54%

시약·촉매·용매 4

HCID 2733548Bis(pinacolato)diborane시약HCID 1349566232-Pyridin-2-yl-5-[2-[4-(trifluoromethyl)-1,3,2-dioxaborolan-2-yl]phenyl]pyridine시약HCID 76001521Bis(1,5-cyclooctadiene)dimethoxydiiridium촉매HCID 7809P-Xylene용매

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온도
55 °C

실험 절차

Ligand 3f: A mixture of ortho- and meta-borylated products (91 mg, 64% yield, ortho/meta + para = 5.1); ortho-borylated product 4n was obtained by further purification by GPC (60 mg, 42% yield), colorless oil;

출처 및 근거

ORD 기록
ord-6861f89fef964ee69d79922c8ba7d19d
출처 데이터셋
Borylation dataset from Roche
DOI
10.1002/anie.201610041

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