Diethyl butylmalonate → 4-n-Butyl-1-[4-(3-methoxyprop-1-ynyl)phenyl]-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octane

HRID 1491599

반응식

HRID 1491599 반응식
[CH2:1](C(C(OCC)=O)C(OCC)=O)CCC.[CH3:16][O:17][CH2:18][C:19]#[C:20][C:21]1[CH:26]=[CH:25][C:24]([C:27]23[O:34][CH2:33][C:30]([CH2:35][CH2:36][CH3:37])([CH2:31][O:32]2)[CH:29]([C:38]([F:41])([F:40])[F:39])[O:28]3)=[CH:23][CH:22]=1>>[CH2:35]([C:30]12[CH2:33][O:34][C:27]([C:24]3[CH:23]=[CH:22][C:21]([C:20]#[C:19][CH2:18][O:17][CH3:16])=[CH:26][CH:25]=3)([O:32][CH2:31]1)[O:28][CH:29]2[C:38]([F:41])([F:39])[F:40])[CH2:36][CH2:37][CH3:1]

참가 물질

3

반응물 2

HCID 67244Diethyl butylmalonateHCID 150219841-[4-(3-Methoxyprop-1-ynyl)phenyl]-4-n-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octane

생성물 1

HCID 150219904-n-Butyl-1-[4-(3-methoxyprop-1-ynyl)phenyl]-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octane

실험 절차

4-n-Butyl-1-[4-(3-methoxyprop-1-ynyl)phenyl]-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octane was prepared from diethyl n-butyl-malonate in a manner analogous to the synthesis of 1-[4-(3-methoxyprop-1-ynyl)phenyl]-4-n-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2,2,2]octane

출처 및 근거

ORD 기록
ord-5bb65366ff6144e09b051637e66fa228
출처 데이터셋
uspto-grants-1994_12
특허 번호
US05371075

연결된 노트

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