Thionyl Chloride → 2-Amino-3-nitrobenzoyl chloride

반응식

[NH2:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](O)=[O:5].S(Cl)([Cl:16])=O>>[NH2:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([Cl:16])=[O:5]

참가 물질

반응물 2

HCID 24386Thionyl Chloride

HCID 2196332-Amino-3-nitrobenzoic acid

생성물 1

HCID 212519672-Amino-3-nitrobenzoyl chloride수율 100%

실험 절차

A mixture of 9.90 parts of 2-amino-3-nitrobenzoic acid and 32.4 parts of thionyl chloride was stirred for 15 min at reflux temperature under argon. The excess of thionyl chloride was evaporated, yielding 10.8 parts (100%) of 2-amino-3-nitrobenzoyl chloride (interm. 39).

후처리

temperatureat reflux temperature under argon
customThe excess of thionyl chloride was evaporated

출처 및 근거

ORD 기록: ord-80550d19bae04b9e93fce46bcb97b910
출처 데이터셋: uspto-grants-1994_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05371079

반응 노트

불러오는 중…