Methylamine → N-methyl-5-nitropyridin-2-amine
반응식
[N+:1]([C:4]1[CH:5]=[N:6][C:7](Cl)=[CH:8][CH:9]=1)([O-:3])=[O:2].[CH3:11][NH2:12]>C(O)C>[N+:1]([C:4]1[CH:5]=[N:6][C:7]([NH:12][CH3:11])=[CH:8][CH:9]=1)([O-:3])=[O:2]참가 물질
4
실험 절차
3-Nitro-6-chloropyridine (5 g, 31.5 mmol) was added to 10 ml of a 30% solution of methylamine in ethanol, followed by reaction at room temperature for 5 minutes. Then, recrystallization from chloroform-hexane gave 4.92 g of the intended product as yellow crude crystals.
후처리
- customfollowed by reaction at room temperature for 5 minutes
- customThen, recrystallization from chloroform-hexane
출처 및 근거
- ORD 기록
- ord-17e25676ecc8440e988f23d60e2f8696
- 출처 데이터셋
- uspto-grants-1994_12
- 특허 번호
- US05371086
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