HCID 3824885, 화합물 → 7-Amino-3,3-dimethyl-3,4-dihydroquinoxalin-2(1H)-one

HRID 1492133노트

반응식

HRID 1492133 반응식
[CH3:1][C:2]1([CH3:16])[C:11](=[O:12])[NH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([N+:13]([O-])=O)[CH:8]=2)[NH:3]1>CO.[Pd]>[NH2:13][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[NH:3][C:2]([CH3:1])([CH3:16])[C:11](=[O:12])[NH:10]2

참가 물질

4

반응물 1

HCID 3824885HCID 3824885, 화합물

생성물 1

HCID 152257137-Amino-3,3-dimethyl-3,4-dihydroquinoxalin-2(1H)-one

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

A solution of 1,2-dihydro-2,2-dimethyl-6-nitro-3-(4H)-quinoxalinone(663 mg, 3 mmol) in CH3OH (10 ml) is hydrogenated with 50 psi H2 (g) at room temperature in the presence of a catalyst of 10% by weight palladium on charcoal (50 mg). After the starting material is consumed, the solution is filtered and concentrated in vacuo to yield 6-amino-1,2-dihydro-2,2-dimethyl-3-(4H) -quinoxalinone.

후처리

  1. customAfter the starting material is consumed
  2. filtrationthe solution is filtered
  3. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-5150eaeb7bf14b3f922ff0a58c85a517
출처 데이터셋
uspto-grants-1994_12
특허 번호
US05373010

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