(2-(Methylthio)ethyl)amine → HCID 178503813, 화합물

HRID 1492244노트

반응식

HRID 1492244 반응식
I.CS[C:4](=[NH:18])[NH:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[N:12]1[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1.[CH3:19][S:20][CH2:21][CH2:22][NH2:23]>C(O)C>[CH3:19][S:20][CH2:21][CH2:22][NH:23][C:4]([NH2:18])=[N:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[N:12]1[CH2:13][CH2:14][O:15][CH2:16][CH2:17]1

참가 물질

4

반응물 2

HCID 87697(2-(Methylthio)ethyl)amineHCID 178503978HCID 178503978, 화합물

생성물 1

HCID 178503813HCID 178503813, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of 2-methyl-1-(2-morpholinophenyl)-2-thiopseudourea hydroiodide (1.7 g) prepared as described in Example 166, 2-methylthioethylamine (1.8 g) and ethanol (25 ml) was heated at 90°-95° C. for 22 hours to give 1-(2-methylthioethyl)-2-(2-morpholinophenyl)guanidine (m.p. 115°-116° C.) which was recrystallised from hexane.

후처리

  1. customprepared
  2. temperaturewas heated at 90°-95° C. for 22 hours

출처 및 근거

ORD 기록
ord-170d2265effa46d3a758d8be2564e12b
출처 데이터셋
uspto-grants-1994_12
특허 번호
US05373008

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