Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Allyl bromide → 4-Allyloxy-3-allylbenzoic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Allyl bromide | HCID 7841 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Methyl 3-allyl-4-hydroxybenzoate | HCID 939882 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 4-Allyloxy-3-allylbenzoic acid methyl ester | HCID 11241748 | 87% |
반응 단계
A solution of 3.04 g (15.8 mmol) of methyl 4-hydroxy-3-propenylbenzoate (Example 7, Step B) was refluxed with anhydrous potassium carbonate (4.37 g, 2 equiv) and allyl bromide (3.5 mL. 2.5 equiv) in acetone overnight. The mixture was filtered through celite and the filter cake was washed with more acetone and dichloromethane. After removing the solvents, the resulting oil was distilled under high vacuum to give 3.2 g (87%) of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05374638 |
| 출처 데이터셋 | uspto-grants-1994_12 |
| ORD ID | ord-a9313012b2f845a988c69a43cfbde043 |
| 출처 메모 | uspto-grants-1994_12 |