Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Butylamine → 4-Butylamino-1-cyclohexyloxy-2,2,6,6-tetramethylpiperidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Butylamine | HCID 8007 | — |
| 반응물 | N-cyclohexyloxy-4-oxo-2,2,6,6-tetramethylpiperidine | HCID 22019868 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Platinum oxide (PtO) | HCID 82844 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4-Butylamino-1-cyclohexyloxy-2,2,6,6-tetramethylpiperidine | HCID 21182129 | 93% |
반응 단계
A mixture of 9.5 grams (37.5 mmol) of 1-cyclohexyloxy-2, 2,6,6-tetramethylpiperidin-4-one, 13.7 grams (187 mmol) of n-butylamine, 0.4 gram of platinum oxide, and 120 ml of ethanol is hydrogenated on a Parr apparatus (50 psi, ambient temperature) till hydrogen uptake ceases. The catalyst is removed by filtration and the filtrate is evaporated to afford 10.8 grams (93% yield) of the title compound as a colorless syrup.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05021481 |
| 출처 데이터셋 | uspto-grants-1991_06 |
| ORD ID | ord-92bc46701d1a47ceb4a90b541d5d45f2 |
| 출처 메모 | uspto-grants-1991_06 |