2-(Trifluoromethyl)benzenepropanoic acid → 7-Bromo-1'-(3-(2-(trifluoromethyl)phenyl)propanoyl)spiro[isoindoline-1,4'-piperidin]-3-one
반응식
[Br:16][c:17]1[cH:18][cH:19][cH:20][c:21]2[c:25]1[C:24]1([NH:23][C:22]2=[O:31])[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]1.[F:1][C:2]([c:3]1[c:4]([CH2:9][CH2:10][C:11](=[O:12])[OH:13])[cH:5][cH:6][cH:7][cH:8]1)([F:14])[F:15]>>[F:1][C:2]([c:3]1[c:4]([CH2:9][CH2:10][C:11](=[O:13])[N:28]2[CH2:27][CH2:26][C:24]3([NH:23][C:22](=[O:31])[c:21]4[cH:20][cH:19][cH:18][c:17]([Br:16])[c:25]43)[CH2:30][CH2:29]2)[cH:5][cH:6][cH:7][cH:8]1)([F:14])[F:15]참가 물질
3
출처 및 근거
- ORD 기록
- ord-66162be733fa404da323ba881467a759
- 출처 데이터셋
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
반응 노트
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