Cyclopropanecarbohydrazide → Cyclopropanecarboxylic acid [1-(6-chloro-3-pyridinyl)ethylidene]hydrazide

HRID 1493720노트

반응식

HRID 1493720 반응식
[C:1]([C:4]1[CH:5]=[N:6][C:7]([Cl:10])=[CH:8][CH:9]=1)(=O)[CH3:2].[CH:11]1([C:14]([NH:16][NH2:17])=[O:15])[CH2:13][CH2:12]1>C(O)C>[Cl:10][C:7]1[N:6]=[CH:5][C:4]([C:1](=[N:17][NH:16][C:14]([CH:11]2[CH2:13][CH2:12]2)=[O:15])[CH3:2])=[CH:9][CH:8]=1

참가 물질

4

반응물 2

HCID 81396CyclopropanecarbohydrazideHCID 27796981-(6-Chloropyridin-3-yl)ethan-1-one

생성물 1

HCID 53866309Cyclopropanecarboxylic acid [1-(6-chloro-3-pyridinyl)ethylidene]hydrazide

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Following the general method of procdure 53 and making non-critical variations, except the product was purified by recrystallization from absolute ethanol rather than by chromotography, 5.25 gm (0.0337 mole) of 3-acetyl-6-chloropyridine and 3.40 gm (0.034 mole) of cyclopropanecarboxylic acid hydrazide yield 6.52 gm (81%) of the title compound having a melting point of 218.1° C.

출처 및 근거

ORD 기록
ord-54bc07b8d87242b88627e816897b5648
출처 데이터셋
uspto-grants-1991_06
특허 번호
US05023334

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