Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 2,2-Difluoro-1-methylcyclopropane-1-carbonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 2,2-Difluoro-1-methylcyclopropane-1-carboxylic acid | HCID 14695229 | — |
| 생성물 | 2,2-Difluoro-1-methylcyclopropane-1-carbonyl chloride | HCID 14695232 | 77% |
반응 단계
A mixture of 250 g (1.8 mol) of 2,2-difluoro-1-methylcyclopropanecarboxylic acid and 700 ml of thionyl chloride is slowly heated in a distillation apparatus, during which process excess thionyl chloride distills over first and the desired product later. In this manner, 215 g (77% of theory) of 2,2-difluoro-1-methyl-cyclopropanecarbonyl chloride are obtained in form of a liquid of boiling point 121°-122° C. ##STR56##
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05025030 |
| 출처 데이터셋 | uspto-grants-1991_06 |
| ORD ID | ord-7b2d3e43e06f4fceb5f1a24097227d99 |
| 출처 메모 | uspto-grants-1991_06 |