Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(2-(Butylthio)2-methylpropylamino]-1-(2-mercapto-2-methylpropylamino)benzene → 2-Propanethiol, 1-anilino-2-methyl-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(2-(Butylthio)2-methylpropylamino]-1-(2-mercapto-2-methylpropylamino)benzene | HCID 10026859 | — |
| 촉매 | Sodium pertechnetate | HCID 74086836 | — |
| 생성물 | 2-Propanethiol, 1-anilino-2-methyl- | HCID 143163 | — |
반응 단계
2-(2-(Butylthio)2-methylpropylamino]-1-(2-mercapto-2-methylpropylamino)benzene was reacted with Tc-99m sodium pertechnetate by the method of Example 7 to produce Tc-99m complex of 2-(2-butylthio)2-methylpropylamino)-1-(2-mercapto-2-methylpropylamino)benzene. The complex was purified by filtration through Millex GS and Jelco 5 micron filters. HPLC (90% ethanol/H 2 O, 1.5 ml/min, C18 5 micron Radial Pak) Rt 4.4 min (99%). TLC (50% diethyl ether/chloroform) Rf 0.89, radiochemical purity 92%. Electrophoresis (0.05 M NaH2PO4, buffer pH 4.5 constant 300 volts, 30 min) neutral.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05026913 |
| 출처 데이터셋 | uspto-grants-1991_06 |
| ORD ID | ord-30d7736693e04af7adb57249130b6cf8 |
| 출처 메모 | uspto-grants-1991_06 |