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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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Pyridinium hydrochloride → (2'r,4'r,6s,10r,13s)-2'-Acetyl-2',6,10,13-tetramethyl-7,8,10,12,13,14,15,16-octahydrospiro[cyclopenta[a]phenanthrene-17,4'-[1,3]dioxane]-3,5'(6h)-dione

HRID 1496720
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HRID 1496720 반응식
[C:1]([O:4][CH2:5][C:6]([C:8]1(O)[C@:24]2([CH3:25])[CH:11]([CH:12]3[C:21](=[CH:22][CH2:23]2)[C@:20]2([CH3:26])[C:15](=[CH:16][C:17](=[O:27])[CH:18]=[CH:19]2)[C@@H:14]([CH3:28])[CH2:13]3)[CH2:10][CH2:9]1)=[O:7])(=[O:3])[CH3:2].[C:30]([O-])([O-])([O:32]CC)[CH3:31].Cl.[NH+]1C=CC=CC=1>C1(C)C=CC=CC=1>[C:30]([C@@:1]1([CH3:2])[O:3][C@:8]2([C@:24]3([CH3:25])[CH:11]([CH:12]4[C:21](=[CH:22][CH2:23]3)[C@:20]3([CH3:26])[C:15](=[CH:16][C:17](=[O:27])[CH:18]=[CH:19]3)[C@@H:14]([CH3:28])[CH2:13]4)[CH2:10][CH2:9]2)[C:6](=[O:7])[CH2:5][O:4]1)(=[O:32])[CH3:31]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

5

반응물 3

HCID 21584435Pyridinium hydrochlorideHCID 672842222-((6s,10r,13s)-17-Hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,10,12,13,14,15,16,17-decahydro-3h-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetateHCID 86598186Ethyl ortho-acetate

생성물 1

HCID 67286271(2'r,4'r,6s,10r,13s)-2'-Acetyl-2',6,10,13-tetramethyl-7,8,10,12,13,14,15,16-octahydrospiro[cyclopenta[a]phenanthrene-17,4'-[1,3]dioxane]-3,5'(6h)-dione

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

2-((6S,10R,13S)-17-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate is dissolved in toluene and heated with 1.5 equivalents of ethyl orthoacetate and a trace of pyridinium hydrochloride. Ethanol is distilled off the reaction mixture to drive it to completion.

후처리

  1. distillationEthanol is distilled off the reaction mixture

출처 및 근거

ORD 기록
ord-53cb4cc4f8e44a77bff0acc53b44c73f
출처 데이터셋
uspto-grants-2015_12
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US09198921B2

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