(2-Amino-4-chlorophenyl)(2-fluorophenyl)methanone → HCID 86682926, 화합물

반응식

[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[F:17])=O.[CH3:18][O:19][C:20](=[O:27])[CH2:21][C:22]([CH:24]1[CH2:26][CH2:25]1)=O>>[CH3:18][O:19][C:20]([C:21]1[C:22]([CH:24]([CH3:26])[CH3:25])=[N:1][C:2]2[C:3]([C:9]=1[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[F:17])=[CH:4][CH:5]=[C:6]([Cl:8])[CH:7]=2)=[O:27]

참가 물질

반응물 2

HCID 2735887(2-Amino-4-chlorophenyl)(2-fluorophenyl)methanone

HCID 101300163-Cyclopropyl-3-Oxopropionic Acid Methyl Ester

생성물 1

HCID 86682926HCID 86682926, 화합물

실험 절차

The title compound was prepared in analogy to example 6 step A from a mixture of (2-amino-4-chloro-phenyl)-(2-fluoro-phenyl)-methanone and 3-cyclopropyl-3-oxo-propionic acid methyl ester. White solid. MS (ESI): 356.1 (M+H)+.

출처 및 근거

ORD 기록: ord-dd2208544e514778a27b67e65a83d0b1
출처 데이터셋: uspto-grants-2015_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09199938B2

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