2-Methylpyrrolidine → HCID 71556620, 화합물

HRID 1497126노트

반응식

HRID 1497126 반응식
C[O:2][C:3]([C:5]1[C:6](Cl)=[N:7][C:8]2[C:13]([C:14]=1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[CH:12][C:11]([Cl:21])=[CH:10][C:9]=2[Cl:22])=[O:4].[CH3:24][CH:25]1[CH2:29][CH2:28][CH2:27][NH:26]1>>[Cl:21][C:11]1[CH:12]=[C:13]2[C:8](=[C:9]([Cl:22])[CH:10]=1)[N:7]=[C:6]([N:26]1[CH2:27][CH2:28][CH2:29][CH:25]1[CH3:24])[C:5]([C:3]([OH:2])=[O:4])=[C:14]2[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

참가 물질

3

반응물 2

HCID 130032-MethylpyrrolidineHCID 86682943HCID 86682943, 화합물

생성물 1

HCID 71556620HCID 71556620, 화합물

실험 절차

The title compound was prepared in analogy to example 21 step D from 2,6,8-trichloro-4-phenyl-quinoline-3-carboxylic acid methyl ester (prepared as described in example 21 step C) and 2-methylpyrrolidine. Brown foam. MS (ESI): 401.2 (M+H)+.

출처 및 근거

ORD 기록
ord-291322f73b5748e589c6b943be532738
출처 데이터셋
uspto-grants-2015_12
특허 번호
US09199938B2

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