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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1497598생성일: 2026년 10월 26일

1-(Phenylmethyl)-1H-indazol-5-amine → (1-benzyl-1H-indazol-5-yl)-(6-iodo-7-fluoroquinazolin-4-yl)-amine hydrochloride

https://huagongshe.com/reaction/1497598

반응식

참여 물질

역할이름HCID투입량
반응물1-(Phenylmethyl)-1H-indazol-5-amineHCID 212069—
반응물4-Chloro-7-fluoro-6-iodoquinazolineHCID 21952006—
생성물(1-benzyl-1H-indazol-5-yl)-(6-iodo-7-fluoroquinazolin-4-yl)-amine hydrochlorideHCID 21952244—

반응 단계

Prepared according to Procedure A from 1-benzyl-1H-indazol-5-ylamine and 4-chloro-6-iodo-7-fluoroquinazoline. δH (400 MHz, DMSO-d6): 11.55 (s, 1H), 9.41 (d, 1H), 8.8 (s, 1H), 8.18 (s, 1H), 8.05 (d, 1H), 7.78 (d, 1H), 7.69 (d, 1H), 7.61 (m, 1H), 7.29 (m, 2H), 7.23 (m, 3H), 5.67 (s, 2H). ESI-MS m/z 496 (M+1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09199973B2
출처 데이터셋uspto-grants-2015_12
ORD IDord-903a36500a2c4cd89e9e23e49f7a35c6
출처 메모uspto-grants-2015_12