Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-bromobutanimide → (2-Amino-5-bromophenyl)(4-chlorophenyl)methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 2-Amino-4'-chlorobenzophenone | HCID 76166 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | (2-Amino-5-bromophenyl)(4-chlorophenyl)methanone | HCID 182477 | — |
반응 단계
To a solution of (2-Amino-phenyl)-(4-chloro-phenyl)-methanone (9.41 g, 0.04 mmol) dissolved in 150 mL DCM was added NBS (7.25 g, 0.04mol) at 0° C. The mixture is stirred at RT for overnight. The mixture is extracted with DCM, washed with NaHCO3, dried over NaSO4 and concentrated. This provides the desired compound. This is used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09199988B2 |
| 출처 데이터셋 | uspto-grants-2015_12 |
| ORD ID | ord-7e3a8be07b7c4d17aec8283a2b9f3b27 |
| 출처 메모 | uspto-grants-2015_12 |