Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-(Methylsulphonyl)benzoic acid → N-[6-[2-(4-Cyano-phenyl)-2H-pyrazol-3-yl]-7-methyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-4-methanesulfonyl-benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-(Methylsulphonyl)benzoic acid | HCID 77670 | — |
| 반응물 | 4-{5-[2-Amino-7-methyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-pyrazol-1-yl}-benzonitrile | HCID 73050976 | — |
| 생성물 | N-[6-[2-(4-Cyano-phenyl)-2H-pyrazol-3-yl]-7-methyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-4-methanesulfonyl-benzamide | HCID 73051753 | — |
반응 단계
The title compound was prepared from 4-{5-[2-amino-7-methyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-pyrazol-1-yl}-benzonitrile (Ex. 1, 100 mg, 0.218 mmol) and 4-(methylsulfonyl)benzoic acid (56.7 mg, 0.283 mmol) using a similar method to that employed for Example 14 (3%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09199984B2 |
| 출처 데이터셋 | uspto-grants-2015_12 |
| ORD ID | ord-32da5806f6f14842bce6c4f47f6a2788 |
| 출처 메모 | uspto-grants-2015_12 |