Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Propanal → (2S,3R)-3-(4-Bromophenyl)-2-methyl-4-nitrobutanal
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Propanal | HCID 527 | — |
| 반응물 | Isopropanol | HCID 3776 | — |
| 반응물 | Hexane | HCID 8058 | — |
| 반응물 | trans-4-Bromo-beta-nitrostyrene | HCID 688204 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | (2S,3R)-3-(4-Bromophenyl)-2-methyl-4-nitrobutanal | HCID 42642902 | — |
반응 단계
The title compound was prepared from propionaldehyde and (E)-1-bromo-4-(2-nitrovinyl)benzene according to the general procedure. Both enantiomeric excess and diastereomeric ratio were determined by HPLC with an AD-H column at 230 nm (2-propanol:hexane=5:95), 1.0 mL/min; major enantiomer tmajor=18.59 min, tminor=13.77 min. [α]D20=−24.6 (c=2.1, CHCl3).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09206090B2 |
| 출처 데이터셋 | uspto-grants-2015_12 |
| ORD ID | ord-9faa47b78e444b0f9145630e53e6a0ed |
| 출처 메모 | uspto-grants-2015_12 |