3,3,3-Trifluoropropylamine → HCID 63226205, 화합물

반응식

[Cl:1][C:2]1[CH:3]=[C:4]([NH2:16])[C:5](N[C@@H]2CCS(=O)(=O)C2)=[CH:6][CH:7]=1.[F:17][C:18]([F:23])([F:22])[CH2:19][CH2:20][NH2:21]>>[Cl:1][C:2]1[CH:3]=[C:4]([NH2:16])[C:5]([NH:21][CH2:20][CH2:19][C:18]([F:23])([F:22])[F:17])=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 100013,3,3-Trifluoropropylamine

HCID 93022115HCID 93022115, 화합물

생성물 1

HCID 63226205HCID 63226205, 화합물

실험 절차

4-Chloro-N1-(3,3,3-trifluoropropyl)benzene-1,2-diamine was prepared in analogy to 4-chloro-N—((R)-1,1-dioxo-tetrahydro-1λ6-thiophen-3-yl)-benzene-1,2-diamine in Example 2-1 by using 3,3,3-trifluoropropan-1-amine instead of (R)-1,1-dioxo-tetrahydro-1λ6-thiophen-3-ylamine.

출처 및 근거

ORD 기록: ord-a5aa579d1a924bf9b3e5e8aa705f1cdd
출처 데이터셋: uspto-grants-2015_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09206191B2

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