3-Methyl-2-(5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-one → 2-(4-(Methoxymethyl)-5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-one
반응식
[CH3:1][O:2][CH2:3][C:4]1[C:8](=[O:9])[O:7][CH2:6][C:5]=1[N:10]1[CH2:14][CH2:13][C:12]2([CH2:19][CH2:18][N:17](C(OC(C)(C)C)=O)[CH2:16][CH2:15]2)[C:11]1=[O:27].CC1CC2(CCNCC2)C(=O)N1C1COC(=O)C=1>>[CH3:1][O:2][CH2:3][C:4]1[C:8](=[O:9])[O:7][CH2:6][C:5]=1[N:10]1[CH2:14][CH2:13][C:12]2([CH2:15][CH2:16][NH:17][CH2:18][CH2:19]2)[C:11]1=[O:27]참가 물질
3
반응물 2
생성물 1
실험 절차
The title compound was prepared from tert-butyl 2-(4-(methoxymethyl)-5-oxo-2,5-dihydrofuran-3-yl)-1-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate in an analogous fashion as described for 3-methyl-2-(5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-one (I-22, last step).
출처 및 근거
- ORD 기록
- ord-c1c647f640e94a74ae3595384d3a6187